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Evolution and Selection of Quantitative Traits$
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Bruce Walsh and Michael Lynch

Print publication date: 2018

Print ISBN-13: 9780198830870

Published to Oxford Scholarship Online: September 2018

DOI: 10.1093/oso/9780198830870.001.0001

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Maintenance of Quantitative Genetic Variation

Maintenance of Quantitative Genetic Variation

Chapter:
(p.1015) 28 Maintenance of Quantitative Genetic Variation
Source:
Evolution and Selection of Quantitative Traits
Author(s):

Bruce Walsh

Michael Lynch

Publisher:
Oxford University Press
DOI:10.1093/oso/9780198830870.003.0028

One of the major unresolved issues in quantitative genetics is what accounts for the amount of standing genetic variation in traits. A wide range of models, all reviewed in this chapter, have been proposed, but none fit the data, either giving too much variation or too little apparent stabilizing selection.

Keywords:   apparent stabilizing selection, balancing selection, house-of-cards model, House-of-Gauss model, Hill-Keightley pleiotropic side-effects model, joint-effects model, Kimura-Lande-Fleming model, Latter-Bulmer model, pleiotropic overdominance, stabilizing selection, stochastic house-of-cards model

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