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Hemoglobin - Insights into protein structure, function, and evolution | Oxford Scholarship Online
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Hemoglobin: Insights into protein structure, function, and evolution

Jay F. Storz

Abstract

The aims of this book are to provide a synthesis of our current understanding of hemoglobin structure, function, and evolution, and to illustrate how research on this paradigmatic protein has provided general insights into mechanisms of molecular evolution and biochemical adaptation. The book promotes an appreciation of how mechanistic insights into protein function can enrich our understanding of how evolution works and, reciprocally, it highlights how approaches in evolutionary genetics (such as phylogenetic comparative methods and ancestral sequence reconstruction) can be brought to bear on ... More

Keywords: adaptation, biochemical adaptation, gene duplication, globin, hemoglobin, hypoxia, oxygen transport, red blood cell, molecular evolution, protein evolution

Bibliographic Information

Print publication date: 2018 Print ISBN-13: 9780198810681
Published to Oxford Scholarship Online: December 2018 DOI:10.1093/oso/9780198810681.001.0001

Authors

Affiliations are at time of print publication.

Jay F. Storz, author
Susan J. Rosowski Professor of Biology, School of Biological Sciences, University of Nebraska, USA