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DepressionLaw and Ethics$
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Charles Foster and Jonathan Herring

Print publication date: 2017

Print ISBN-13: 9780198801900

Published to Oxford Scholarship Online: October 2017

DOI: 10.1093/oso/9780198801900.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2019. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 19 November 2019

The Treatment of Depression

The Treatment of Depression

An Overview of the Physical Options

(p.103) 10 The Treatment of Depression

Hugh Series

Oxford University Press

This chapter considers some of the physical options for the treatment of the affective disorders, depression, and mania. It first provides an historical overview of physical treatments for depression, including drugs such as opium, morphine, and diamorphine, chloral, and barbiturates, as well as electroconvulsive therapy (ECT). It then examines whether antidepressants work and how they are used before describing the biological basis of depression. It also looks at different classes of antidepressants, including monoamine oxidase inhibitors (MAOIs), reuptake inhibitors, and mood stabilizers. Finally, it evaluates non-pharmacological physical treatments ranging from ECT to transcranial magnetic stimulation (TMS), psychosurgery and deep brain stimulation, and novel therapies.

Keywords:   affective disorders, depression, mania, physical treatment, drugs, electroconvulsive therapy, antidepressants, transcranial magnetic stimulation, psychosurgery, deep brain stimulation

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