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Single-Molecule Studies of Nucleic Acids and Their Proteins$
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David Bensimon, Vincent Croquette, Jean-François Allemand, Xavier Michalet, and Terence Strick

Print publication date: 2018

Print ISBN-13: 9780198530923

Published to Oxford Scholarship Online: February 2019

DOI: 10.1093/oso/9780198530923.001.0001

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Single-Molecule Studies of DNA-Associated Motors

Single-Molecule Studies of DNA-Associated Motors

(p.119) 6 Single-Molecule Studies of DNA-Associated Motors
Single-Molecule Studies of Nucleic Acids and Their Proteins

David Bensimon

Vincent Croquette

Jean-François Allemand

Xavier Michalet

Terence Strick

Oxford University Press

This chapter provides a quick introduction to the various uses of single-molecule approaches in the study of DNA–protein interactions. This field is a rapidly evolving one and we have not attempted to cover it in any systematic way. In the following chapters we provide examples of the type of questions addressed in the study of the interactions of DNA with three families of molecular motors: polymerases, helicases, and topoisomerases.

Keywords:   DNA–protein interactions, single-molecule studies

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