Jump to ContentJump to Main Navigation
The Science of Marijuana$
Users without a subscription are not able to see the full content.

Leslie Iversen

Print publication date: 2019

Print ISBN-13: 9780190846848

Published to Oxford Scholarship Online: November 2018

DOI: 10.1093/oso/9780190846848.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2019. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 16 October 2019

Endocannabinoids

Endocannabinoids

Chapter:
(p.99) Chapter 4 Endocannabinoids
Source:
The Science of Marijuana
Author(s):

Leslie Iversen

Publisher:
Oxford University Press
DOI:10.1093/oso/9780190846848.003.0004

The endocannabinoids are part of a large family of lipid signaling molecules derived from arachidonic acid, including the prostaglandins and leukotrienes, which are important mediators of inflammation. Far less is known about the newer members of the endocannabinoid group, and it remains unclear whether they all play important functional roles. This chapter reviews the multiple members of this family and their biosynthesis and inactivation. Physiological functions, including retrograde synaptic signaling, control of energy metabolism, regulation of pain sensitivity, and cardiovascular control, are discussed. In addition, the chapter reports the synthesis of novel agonists, antagonists, and compounds inhibiting endocannabinoid inactivation as novel medicines.

Keywords:   anandamide, retrograde synaptic signaling, cardiovascular control, cannabinoids, endocannabinoids

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .