Jump to ContentJump to Main Navigation
Estrogens and MemoryBasic Research and Clinical Implications$
Users without a subscription are not able to see the full content.

Karyn M. Frick

Print publication date: 2020

Print ISBN-13: 9780190645908

Published to Oxford Scholarship Online: February 2020

DOI: 10.1093/oso/9780190645908.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 02 June 2020

Ovarian Hormones, Cognition, and Reproductive Aging

Ovarian Hormones, Cognition, and Reproductive Aging

Applications and Implications for Translating Preclinical Endocrine Brain Research to the Clinic

(p.223) 14 Ovarian Hormones, Cognition, and Reproductive Aging
Estrogens and Memory

Alesia V. Prakapenka

Veronica L. Peña

Heather A. Bimonte-Nelson

Oxford University Press

Increasing evidence has demonstrated that sex steroid hormones, such as estrogens and progestogens, impact nonreproductive behaviors such as cognitive function in women and nonhuman animals. In addition to cognitive alterations associated with the reproductive cycle in young females, endocrine changes in middle-aged and aged females can impact cognition in ways that may increase risk of dementia and neurodegenerative disease. As such, understanding how aging and reproductive senescence influence cognitive functions like memory, and whether hormone therapy can mitigate these effects, is extremely important to maintaining women’s mental health. This chapter reviews the endocrine changes that occur at reproductive senescence in women and rodents, describes rodent models of menopause and memory assessment and discusses the effects of various hormone therapies on learning and memory in aging females. Various factors influencing the effects of hormone therapy on cognition are discussed, as are considerations for future research.

Keywords:   estrogens, estrogen therapy, progestogens, memory, cognition, aging, menopause, reproductive senescence, animal models

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .