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Cancer Epidemiology and Prevention$
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Michael Thun, Martha S. Linet, James R. Cerhan, Christopher A. Haiman, and David Schottenfeld

Print publication date: 2017

Print ISBN-13: 9780190238667

Published to Oxford Scholarship Online: December 2017

DOI: 10.1093/oso/9780190238667.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2019. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 13 November 2019

Regulation

Regulation

Chapter:
(p.1239) 62.6 Regulation
Source:
Cancer Epidemiology and Prevention
Author(s):

Jonathan M. Samet

Lynn Goldman

Publisher:
Oxford University Press
DOI:10.1093/oso/9780190238667.003.0069

This chapter provides a broad overview of governmental regulatory approaches to controlling exposure to carcinogens in air, water, food, drugs, and other consumer products. It covers general principles and approaches and the increasing emphasis on in vitro high-throughput testing to screen chemicals for potential toxicity. It focuses specifically on statutes related to the United States, while giving lesser coverage to approaches in Europe. The focus is at the federal level, even though states may also promulgate regulations. Although epidemiologic evidence and animal testing have historically provided the basis for regulations to limit exposure to environmental carcinogens, it is hoped that alternative testing methods that use high-throughput in vitro screening will accelerate testing of unregulated chemicals and limit reliance on animal bioassays.

Keywords:   carcinogen, toxicity, regulation, California, Proposition 65

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