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Schizophrenia and Its TreatmentWhere Is the Progress?$
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Matthew M. Kurtz

Print publication date: 2015

Print ISBN-13: 9780199974443

Published to Oxford Scholarship Online: December 2015

DOI: 10.1093/acprof:oso/9780199974443.001.0001

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Course and Outcome

Course and Outcome

(p.15) 2 Course and Outcome
Schizophrenia and Its Treatment

Matthew M. Kurtz

Oxford University Press

Initial conceptualization of schizophrenia as a disorder that by definition has a largely downward course is not supported by the extant data. Periods of recovery are very much possible and likely for a significant proportion of patients, and this recovery in a minority of patients is maintained in the absence of pharmacotherapy, but data on the relationship of consistently applied pharmacotherapy to long-term outcome remains sparse. Nonetheless, although improvement over time is common, the level of social disability in many patients remains high. Negative symptoms, and specifically the deficit syndrome, predict poorer long-term outcome and emphasize the need for specialized treatments tailored to the specific needs of this subpopulation. Although initial WHO studies suggested better outcome in schizophrenia in the developing world, more recent studies suggest that psychosocial dysfunction in schizophrenia may be more consistent across cultures than originally thought.

Keywords:   outcome, schizophrenia, recovery, developing world, treatment

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