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The Cognitive Neuroscience of MemoryAn Introduction$
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Howard Eichenbaum

Print publication date: 2011

Print ISBN-13: 9780199778614

Published to Oxford Scholarship Online: May 2012

DOI: 10.1093/acprof:oso/9780199778614.001.0001

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Cellular Mechanisms of Memory: Complex Circuits

Cellular Mechanisms of Memory: Complex Circuits

Chapter:
(p.51) 3 Cellular Mechanisms of Memory: Complex Circuits
Source:
The Cognitive Neuroscience of Memory
Author(s):

Howard Eichenbaum

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199778614.003.0003

This chapter reviews some of the progress toward a full characterization of one particular form of synaptic plasticity observed in the mammalian brain called long-term potentiation (LTP). LTP is only a laboratory phenomenon. Nevertheless, its mechanisms are now quite well understood, it can be induced in many brain structures that are involved in memory, and there is substantial evidence that the same cellular mechanisms that mediate LTP are required for lasting memory. The chapter reviews the state of our understanding of this important phenomenon as a likely candidate for memory coding in mammalian systems.

Keywords:   synaptic plasticity, mammalian brain, long-term potentiation, memory coding

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