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Nutritional Epidemiology$
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Walter Willett

Print publication date: 2012

Print ISBN-13: 9780199754038

Published to Oxford Scholarship Online: January 2013

DOI: 10.1093/acprof:oso/9780199754038.001.0001

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Genetics in Dietary Analyses

Genetics in Dietary Analyses

(p.334) 14 Genetics in Dietary Analyses
Nutritional Epidemiology

Walter Willett

Oxford University Press

Nutritionists have long known that differences exist among individuals in their responses to the same dietary change, and it was assumed that many of these differences were due to unmeasurable genetic factors. These genetic factors can now be measured directly, and the incorporation of genetic markers into studies of diet and disease creates a wealth of opportunities that did not exist even twenty years ago. This chapter discusses the study of gene-diet interactions, the use of genetic markers to inform diet and disease relationships (Mendelian randomization), and the classification of outcomes using genetic characteristics.

Keywords:   genetic factors, genetic markers, gene-diet interactions, disease, mendelian randomization

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