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Engineering the Next Revolution in NeuroscienceThe New Science of Experiment Planning$
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Alcino J. Silva, Anthony Landreth, and John Bickle

Print publication date: 2013

Print ISBN-13: 9780199731756

Published to Oxford Scholarship Online: January 2014

DOI: 10.1093/acprof:oso/9780199731756.001.0001

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Resonating Experiments

Resonating Experiments

Chapter:
(p.95) [6] Resonating Experiments
Source:
Engineering the Next Revolution in Neuroscience
Author(s):

Alcino J. Silva

Anthony Landreth

John Bickle

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199731756.003.0006

Replication of findings is critical and central to science. When similar or even identical experiments are carried out, the results are expected to be compatible and consistent. When they are not, the experiments are deemed unreliable and hypotheses are weakened. Thus, beyond the Convergent 3 and Eliminative Inference Analyses introduced in previous chapters, hypotheses must also pass Consistency Analyses. This type of analysis can be carried out for a singular series of experiments, or for a large number of experiments addressing a key hypothesis, such as the role of synaptic mechanisms in memory. This chapter uses the complex history of neuroscience studies of learning and memory to illustrate some surprising features of Consistency Analyses.

Keywords:   Experiment, replication, learning, memory, long-term potentiation

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