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Handbook of Cannabis$
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Roger Pertwee

Print publication date: 2014

Print ISBN-13: 9780199662685

Published to Oxford Scholarship Online: January 2015

DOI: 10.1093/acprof:oso/9780199662685.001.0001

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The Chemical Phenotypes (Chemotypes) of Cannabis

The Chemical Phenotypes (Chemotypes) of Cannabis

Chapter:
(p.89) Chapter 5 The Chemical Phenotypes (Chemotypes) of Cannabis
Source:
Handbook of Cannabis
Author(s):

Etienne de Meijer

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199662685.003.0005

Chemical phenotypes (chemotypes) of Cannabis are defined by the content and composition of their cannabinoid fraction. This chapter describes the current diversity of chemotypes and discusses their underlying genetic mechanisms and breeding histories. The role of chemotype in Cannabis classification is addressed. Specific morphological features of the glandular trichomes associated with certain chemotypes are illustrated. The purity, content, and yield levels of the cannabinoids of clones selected in a plant-breeding program at GW Pharmaceuticals are presented. Several of these clones are currently in use for pharmaceutical raw material production. Their crude floral extracts and purified cannabinoids are being investigated for therapeutic potential. The chapter closes with some thoughts on the prospects of molecular breeding to modify cannabinoid biogenesis and further expand the cannabinoid portfolio

Keywords:   biogenesis, cannabinoid, Cannabis, chemotype, phenotype, plant-breeding, trichomes

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