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TobaccoScience, policy and public health$
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Peter Boyle, Nigel Gray, Jack Henningfield, John Seffrin, and Witold Zatonski

Print publication date: 2010

Print ISBN-13: 9780199566655

Published to Oxford Scholarship Online: September 2010

DOI: 10.1093/acprof:oso/9780199566655.001.0001

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Smoking, hormone concentrations, and endometrial cancer

Smoking, hormone concentrations, and endometrial cancer

Chapter:
(p.513) Chapter 30 Smoking, hormone concentrations, and endometrial cancer
Source:
Tobacco
Author(s):

Paul D. Terry

Thomas E. Rohan

Elisabete Weiderpass

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199566655.003.0030

This chapter reviews studies on the link between smoking and an endometrial cancer risk, and changes in urinary hormone concentrations that may underlie this smoking-cancer association. The available data suggest that cigarette smoking is associated with a reduced risk of endometrial cancer among current-smokers, mainly among postmenopausal women, and that the association weakens with time since quitting. Studies that examined quantitative measures of exposure to cigarette smoke have shown greater reductions in risk among women who were current-smokers and smoked either more intensely or for a longer duration than women who smoked relatively less. The mechanisms by which this association may be driven remain unclear.

Keywords:   cigarette smoking, endometrial cancer, cancer risk, tobacco use, urinary hormone concentrations

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