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TobaccoScience, policy and public health$
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Peter Boyle, Nigel Gray, Jack Henningfield, John Seffrin, and Witold Zatonski

Print publication date: 2010

Print ISBN-13: 9780199566655

Published to Oxford Scholarship Online: September 2010

DOI: 10.1093/acprof:oso/9780199566655.001.0001

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Smoking and cervical neoplasia

Smoking and cervical neoplasia

Chapter:
(p.445) Chapter 25 Smoking and cervical neoplasia
Source:
Tobacco
Author(s):

Maribel Almonte

Anne Szarewski

and Jack Cuzick

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199566655.003.0025

This chapter reviews studies on the link between smoking and cervical cancer. Epidemiologic evidence strongly links smoking with squamous cell cervical cancer and high-grade cervical intraepithelial neoplasia (CIN). However, some controversy still exists as to whether the link is causal or in some way reflects residual confounding with unmeasured aspects of sexual behaviour, although the case for causality has strengthened considerably in the past few years. Attempts to adjust for sexual behaviour through variables such as age at first intercourse and number of sexual partners have generally reduced the strength of the relationship with smoking, but it has not disappeared: it remains at or above two-fold for current-smokers and shows a dose-response relationship in many studies.

Keywords:   cigarette smoking, cervical cancer, cancer risk, tobacco use

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