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Ancestral Sequence Reconstruction$
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David A Liberles

Print publication date: 2007

Print ISBN-13: 9780199299188

Published to Oxford Scholarship Online: September 2008

DOI: 10.1093/acprof:oso/9780199299188.001.0001

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The resurrection of ribonucleases from mammals: from ecology to medicine

The resurrection of ribonucleases from mammals: from ecology to medicine

Chapter:
(p.208) CHAPTER 18 The resurrection of ribonucleases from mammals: from ecology to medicine
Source:
Ancestral Sequence Reconstruction
Author(s):

Slim O. Sassi

Steven A. Benner

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199299188.003.0018

Ribonucleases, well-known digestive enzymes that supported the development of much of protein science, emerged through an evolutionary history having a rich history of functional recruitment. This chapter reviews paleogenetic studies that explored changing function in this family. Similar approaches promise to be powerful tools to advance medicine in a post-genomic world.

Keywords:   Ribonucleases, digestive enzymes, post-genomic, protein science

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