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Venous Thromboembolism in Advanced DiseaseA clinical guide$
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Simon I R Noble, Miriam J Johnson, and Agnes Y Y Lee

Print publication date: 2008

Print ISBN-13: 9780199232048

Published to Oxford Scholarship Online: November 2011

DOI: 10.1093/acprof:oso/9780199232048.001.0001

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Anticoagulants: current and future therapeutic options

Anticoagulants: current and future therapeutic options

Chapter:
(p.65) Chapter 5 Anticoagulants: current and future therapeutic options
Source:
Venous Thromboembolism in Advanced Disease
Author(s):

Robert Weinkove

Beverley J. Hunt

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199232048.003.0005

This chapter aims to review the pharmacology and use of both the established and the newer anticoagulants used in venous thromboembolism (VTE). These include unfractionated heparin, low molecular weight heparins (LMWH), danaparoid, coumarins, idraparinux, and hirudin. This chapter discusses the history, composition, mechanism of action, dosage, monitoring, reversal, indications and contraindications, and adverse effects of these anticoagulants.

Keywords:   anticoagulants, VTE, unfractionated heparin, low molecular weight herapins, danaparoid, idraparinux, hirudin

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