Jump to ContentJump to Main Navigation
Statistical Theory and Methods for Evolutionary Genomics$
Users without a subscription are not able to see the full content.

Xun Gu

Print publication date: 2010

Print ISBN-13: 9780199213269

Published to Oxford Scholarship Online: January 2011

DOI: 10.1093/acprof:oso/9780199213269.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 31 May 2020

Basics in Molecular Evolution

Basics in Molecular Evolution

(p.1) 1 Basics in Molecular Evolution
Statistical Theory and Methods for Evolutionary Genomics

Xun Gu

Oxford University Press

Molecular evolution is the study of the process of evolution at the level of DNA, RNA, and proteins, in which the neutral or nearly neutral evolution model has provided the theoretical basis. Yet, the role of positive selection at the molecular level remains a controversial issue. Recent advances in genomics, including whole-genome sequencing, high-throughput protein characterization, and bioinformatics have led to a dramatic increase in studies in comparative and evolutionary genomics. This chapter introduces some widely-used methods in genomic analysis. These include distance method, parsimony methods, maximum-likelihood methods, Bayesian methods, and ancestral sequence inference.

Keywords:   molecular evolution, DNA sequences, genomic analysis, evolutionary genomics, phylogenetic trees, phylogenetic inference

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .