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Dendrites$
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Greg Stuart, Nelson Spruston, and Michael Häusser

Print publication date: 2007

Print ISBN-13: 9780198566564

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198566564.001.0001

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RNA targeting, trafficking, and translation in dendrites

RNA targeting, trafficking, and translation in dendrites

Contribution to synaptic tagging and plasticity

Chapter:
(p.116) (p.117) Chapter 5 RNA targeting, trafficking, and translation in dendrites
Source:
Dendrites
Author(s):

Lindy Barrett

James Eberwine

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198566564.003.0005

It is well established that a subset of proteins can be translated in dendrites independently of the cell soma. Recent studies have begun to elucidate the dynamic regulation and functional consequences of this local protein synthesis. In addition to more detailed analyses of mRNA localization, translation, and trafficking in dendrites, new research highlights possible roles of local translation in synaptic plasticity, suggesting a critical role for local translation in neuronal activity.

Keywords:   protein synthesis, dendrites, RNA targeting, mRNA localization, synaptic plasticity, local translation

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