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AppetiteNeural and Behavioural Bases$
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Charles R. Legg and David Booth

Print publication date: 1994

Print ISBN-13: 9780198547877

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198547877.001.0001

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A brief history of the anhedonia hypothesis

A brief history of the anhedonia hypothesis

Chapter:
(p.243) 10 A brief history of the anhedonia hypothesis
Source:
Appetite
Author(s):

Roy A. Wise

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198547877.003.0010

This chapter discusses the history of the so-called anhedonia hypothesis. The term anhedonia was first used in 1978 in connection with the assertion that pimozide blocks the reward quality of food. The anhedonia hypothesis was based largely on studies of psychomotor stimulant, brain stimulation, and food and water reinforcement. It also discusses brain stimulation reward, opiate reinforcement, and several other drugs of abuse that activate the dopamine system.

Keywords:   anhedonia hypothesis, pimozide, quality of food, psychomotor stimulant, brain stimulation, food reinforcement, water reinforcement, opiate reinforcement, dopamine system

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