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Critical Appraisal of Epidemiological Studies and Clinical Trials$
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Mark Elwood

Print publication date: 2007

Print ISBN-13: 9780198529552

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198529552.001.0001

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Chance variation

Chance variation

Chapter:
(p.225) Chapter 7 Chance variation
Source:
Critical Appraisal of Epidemiological Studies and Clinical Trials
Author(s):

J. Mark Elwood

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198529552.003.07

This chapter discusses the effects of chance variation that can be assessed by applying statistical tests. It is divided into three parts: the application of statistical tests and confidence limits to a simple 2 x 2 table; applications to stratified and matched studies, and to multivariate analysis; and life-table methods for the consideration of the timing of outcome events in a cohort study or intervention study. Self-test questions are provided at the end of the chapter.

Keywords:   variation, statistical tests, confidence limits, multivariate analysis, stratification, life-table methods

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