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Coronary Heart Disease EpidemiologyFrom aetiology to public health$
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Michael Marmot and Paul Elliott

Print publication date: 2005

Print ISBN-13: 9780198525738

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198525738.001.0001

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Lipids and cholesterol

Lipids and cholesterol

Chapter:
(p.174) Chapter 12 Lipids and cholesterol
Source:
Coronary Heart Disease Epidemiology
Author(s):

M. R. Law

A. Rodgers

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198525738.003.0012

This chapter discusses the role of lipids and cholesterol in coronary heart disease (CHD). The high levels of serum cholesterol found in Western populations are a major cause of the high mortality from CHD. Realistic dietary change in a community can lower serum cholesterol by 0.6 mmol/l (10%) and reduce heart disease mortality by approximately 25% among middle-aged individuals. Cholesterol-lowering drugs (statins) can lower cholesterol by 1.8 mmol/l (30%), and reduce the risk of heart disease death by approximately 60% from the third year onwards. Statins are inexpensive and safe, and their widespread use should be encouraged.

Keywords:   coronary heart disease, cholesterol-lowering drugs, low-density lipoprotein, high-density lipoprotein, diet, statins

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