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NeuroDynamix IIConcepts of Neurophysiology Illustrated by Computer Simulations$
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W. Otto Friesen and Jonathon Friesen

Print publication date: 2009

Print ISBN-13: 9780195371833

Published to Oxford Scholarship Online: February 2010

DOI: 10.1093/acprof:oso/9780195371833.001.0001

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Soma Model

Soma Model

Chapter:
(p.154) II.3 Soma Model
Source:
NeuroDynamix II
Author(s):

W. Otto Friesen

Jonathon A. Friesen

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195371833.003.0010

The Soma model simulates the origin of the resting potential in nerve cells. Because this model demonstrates steady-state conditions, or slow changes in the steady state, the membrane capacitance is ignored. In addition, there are no voltage- or time-dependent membrane conductances in this model. The equilibrium (Nernst) potentials for sodium, potassium, calcium, and chloride ions are calculated from the relevant ionic concentrations. The relationship between temperature and equilibrium potentials can be explored by altering the simulated temperature. This model also includes an electrogenic pump, which generates a net outflow of positive ions and therefore acts to hyperpolarize the membrane.

Keywords:   parameter, variable, resting potential, Nernst equation, parallel conductance model, electrogenic membrane pump, conductance

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