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Responsible Conduct of Research$
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Adil E Shamoo and David B Resnik

Print publication date: 2009

Print ISBN-13: 9780195368246

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195368246.001.0001

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The Protection of Human Subjects in Research

The Protection of Human Subjects in Research

Chapter:
(p.236) 12 The Protection of Human Subjects in Research
Source:
Responsible Conduct of Research
Author(s):

Adil E. Shamoo

David B. Resnik (Contributor Webpage)

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195368246.003.0012

This chapter discusses the history of human experimentation, with special attention to cases that have helped to shape ethical guidelines and policies. It discusses important codes, such as the Nuremberg Code and the Declaration of Helsinki, and it provides an overview of U.S. federal regulations. The chapter also addresses some key concepts and principles in human research, such as informed consent, risk/benefit ratios, minimal risk, and research versus therapy.

Keywords:   human subject protection, ethical guidelines, policies, Nuremberg Code, Declaration of Helsinki, U.S. federal regulations, informed consent, risk/benefit ratios, minimal risk, research versus therapy

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