Jump to ContentJump to Main Navigation
Cortical Oscillations in Health and Disease$
Users without a subscription are not able to see the full content.

Roger Traub, MD and Miles Whittington, PhD

Print publication date: 2010

Print ISBN-13: 9780195342796

Published to Oxford Scholarship Online: May 2010

DOI: 10.1093/acprof:oso/9780195342796.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 07 April 2020

Schizophrenia

Schizophrenia

Chapter:
(p.123) 6 Schizophrenia
Source:
Cortical Oscillations in Health and Disease
Author(s):

Roger D. Roger

Miles A. Whittington

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195342796.003.0006

One factor in schizophrenia may be a decrease in NMDA receptor mediated excitation of interneurons, both acting during brain development and also more acutely. The NMDA receptor antagonist, ketamine, given to normal volunteers, can elicit psychotic symptoms. Ketamine also affects gamma (30 – 70 Hz) and beta oscillations experimentally, in in vitro brain slices. The effects of ketamine, however – whether to enhance or diminish oscillation power, and acting on which frequency range – depend on the brain region in question. There is no pan-cortical phenomenology of oscillations.

Keywords:   psychosis, interneuron, ketamine, gamma, beta

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .