Jump to ContentJump to Main Navigation
Neuroimaging in Epilepsy$
Users without a subscription are not able to see the full content.

Harry Chugani, MD

Print publication date: 2010

Print ISBN-13: 9780195342765

Published to Oxford Scholarship Online: January 2011

DOI: 10.1093/acprof:oso/9780195342765.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 29 January 2020

Positron Emission Tomography: Glucose Metabolism in Extratemporal Lobe Epilepsy

Positron Emission Tomography: Glucose Metabolism in Extratemporal Lobe Epilepsy

Chapter:
(p.141) Chapter 9 Positron Emission Tomography: Glucose Metabolism in Extratemporal Lobe Epilepsy
Source:
Neuroimaging in Epilepsy
Author(s):

Csaba Juhász

Harry T. Chugani

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195342765.003.0009

The interictal FDG PET often shows focal cortical hypometabolism in patients with extratemporal epilepsy and can correctly regionalize neocortical epileptic foci in more than 2/3 of the cases, even if MRI is non-localizing. In some cases, however, FDG PET overestimates the epileptogenic region, and hypometabolism may extend progressively to involve remote cortical and subcortical regions, thus establishing an epileptic network in chronic epilepsy. On the other hand, hypometabolism can occur adjacent to, rather than completely overlap with, ictal seizure onset zones. Therefore, FDG PET is best used for presurgical evaluation in combination with other clinical, electrophysiological and imaging data to guide intracranial grid placement and optimize tailored neocortical resection. When applied in this manner, the use of FDG PET can improve outcome of extratemporal lobe epilepsy surgery.

Keywords:   extratemporal, epilepsy, FDG-PET, hypometabolism, cortex, neocortical, subcortical, presurgical evaluation, surgery, surgical outcome

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .