Jump to ContentJump to Main Navigation
Imaging the Aging Brain$
Users without a subscription are not able to see the full content.

William Jagust and Mark D'Esposito

Print publication date: 2009

Print ISBN-13: 9780195328875

Published to Oxford Scholarship Online: February 2010

DOI: 10.1093/acprof:oso/9780195328875.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2019. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 20 September 2019

Functional Imaging with FDG-PET in Mild Cognitive Impairment

Functional Imaging with FDG-PET in Mild Cognitive Impairment

Chapter:
(p.183) 13 Functional Imaging with FDG-PET in Mild Cognitive Impairment
Source:
Imaging the Aging Brain
Author(s):

Karl Herholz

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195328875.003.0013

Assessment of regional cerebral glucose metabolism by FDG-PET at the resting state is a standard functional technique to assess cerebral function. An increasing body of evidence indicates that substantial impairment of FDG uptake in temporo-parietal association cortices is a reliable predictor of rapid progression to dementia in patients with mild cognitive impairment (MCI). The definition of affected and reference regions, the methods for quantitative analysis, and other methodological issues that are relevant for use of the method in clinical studies are being addressed. Effects of aging, the selection of normal controls, and interaction with age and genetic risk factors are important factors that also need to be considered in designing and interpreting studies.

Keywords:   positron emission tomography, 18F-fluorodeoxyglucose, cerebral glucose metabolism, standardized image analysis, prediction of progression

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .