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Imaging the Aging Brain$
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William Jagust and Mark D'Esposito

Print publication date: 2009

Print ISBN-13: 9780195328875

Published to Oxford Scholarship Online: February 2010

DOI: 10.1093/acprof:oso/9780195328875.001.0001

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Structural Imaging of Mild Cognitive Impairment

Structural Imaging of Mild Cognitive Impairment

Chapter:
(p.169) 12 Structural Imaging of Mild Cognitive Impairment
Source:
Imaging the Aging Brain
Author(s):

Clifford R. Jack

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195328875.003.0012

This chapter describes the concept of mild cognitive impairment (MCI), the initial construct of amnestic MCI as well as the expanded construct that includes both amnestic and nonamnestic forms. The focus of the chapter is on quantitative magnetic resonance (MR) imaging studies in MCI. While the major emphasis is on structural MRI, other MR imaging techniques such as spectroscopy and diffusion imaging are described in the context of MCI. Specifically, relationships between imaging and clinical features of MCI in cross-sectional and longitudinal contexts are outlined. The chapter also describes the complementary nature of the information provided by MRI and amyloid imaging.

Keywords:   magnetic resonance imaging, quantitative MRI, mild cognitive impairment, amyloid imaging, longitudinal imaging

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