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Obesity Epidemiology$
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Frank Hu

Print publication date: 2008

Print ISBN-13: 9780195312911

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780195312911.001.0001

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Metabolic Consequences of Obesity

Metabolic Consequences of Obesity

Chapter:
(p.149) 8 Metabolic Consequences of Obesity
Source:
Obesity Epidemiology
Author(s):

Frank B. Hu

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195312911.003.0008

This chapter reviews the links between obesity and individual components of the metabolic syndrome as well as underlying biological mechanisms, such as insulin resistance, systemic inflammation, and endothelial dysfunction. It discusses recent epidemiologic studies on risk of diabetes in relation to changes in fat distribution, the role of overall adiposity versus abdominal obesity, and the relative importance of fatness versus fitness. The chapter also examines epidemiologic literature related to “fellow travelers” of the metabolic syndrome.

Keywords:   obesity research, metabolic syndrome, metabolic disorders, insulin resistance, systemic inflammation, endothlial dysfuction, diabetes, adiposity

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