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The Case-Control MethodDesign and Applications$
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Haroutune Armenian

Print publication date: 2009

Print ISBN-13: 9780195187113

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780195187113.001.0001

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Problem Investigation and Inferences Using the Case-Control Method

Problem Investigation and Inferences Using the Case-Control Method

The Case-Control Method

Haroutune K. Armenian

Oxford University Press

This chapter begins by presenting the type of problems that are investigated using the case-control method. These include etiologic research, acute event investigation, and evaluation of health care interventions. Problems of design that may lead to contradictory results between different studies of the same hypothesis are presented prior to a discussion of various aspects of making inferences from case-control studies. The necessity of testing more complex etiological models using the case-control method is discussed, as well as the inferential limitations of investigative data in making decisions about public policy. The final section of the chapter presents a list of eight questions that can help in the design as well as the evaluation of case-control studies.

Keywords:   definitions, false positive results, inferences, complex models

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