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Brain DevelopmentNormal Processes and the Effects of Alcohol and Nicotine$
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Michael W. Miller

Print publication date: 2006

Print ISBN-13: 9780195183139

Published to Oxford Scholarship Online: January 2010

DOI: 10.1093/acprof:oso/9780195183139.001.0001

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Neuronal Migration

Neuronal Migration

Chapter:
(p.27) 3 Neuronal Migration
Source:
Brain Development
Author(s):

Huaiyu Hu

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195183139.003.0003

During the development of the mammalian central nervous system (CNS), neurons are commonly generated at sites far from their final locations. They migrate to an anlage before differentiating into their final morphology and making synaptic connections. This chapter reviews the basic principles of radial and tangential migration, molecular events underlying normal neuronal migration, and some molecular defects that disturb neuronal migration to cause neurological disorders.

Keywords:   central nervous system, neurons, neuronal migration, tangential migration, radial migration

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