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Brain DevelopmentNormal Processes and the Effects of Alcohol and Nicotine$
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Michael W. Miller

Print publication date: 2006

Print ISBN-13: 9780195183139

Published to Oxford Scholarship Online: January 2010

DOI: 10.1093/acprof:oso/9780195183139.001.0001

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Neuronal Survival is Compromised by Ethanol: Extracellular Mediators

Neuronal Survival is Compromised by Ethanol: Extracellular Mediators

Chapter:
(p.245) 15 Neuronal Survival is Compromised by Ethanol: Extracellular Mediators
Source:
Brain Development
Author(s):

Michael W. Miller

Maria B. Bruns

Paula L. Hoffman

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195183139.003.0015

This chapter discusses the effects of ethanol on the incidence of neuronal death and the extracellular mediators that define this death. Ethanol-induced neuronal death occurs during defined periods of the developmental time line. These time periods coincide with those of neuronogenesis and primary synaptogenesis, which are periods of naturally occurring neuronal death (NOND). Exposure of ethanol at this time may exacerbate processes involved in NOND.

Keywords:   ethanol exposure, naturally occurring neuronal death, extracellular mediators

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