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Mind-Altering DrugsThe Science of Subjective Experience$
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Mitch Earleywine

Print publication date: 2005

Print ISBN-13: 9780195165319

Published to Oxford Scholarship Online: April 2010

DOI: 10.1093/acprof:oso/9780195165319.001.0001

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Subjective Effects of Opioids

Subjective Effects of Opioids

(p.217) 8 Subjective Effects of Opioids
Mind-Altering Drugs

Sandy M. Comer

James P. Zacny

Oxford University Press

Opioids, which have long been abused, are capable of producing euphoria and other “positive” subjective effects. Although the relationship between positive subjective effects and abuse of a drug is not necessarily causal, there is a predictive relationship between those drugs that produce a positive spectrum of subjective effects and their likelihood of functioning as reinforcers and being abused. A host of factors influence the subjective effects of opioids (and subsequently their abuse liability); some of the more salient ones are covered in this chapter. It first describes how subjective effects of opioids are measured and then discusses how such factors as dose, route of administration, rate of onset of drug effects, tolerance and dependence, and drug use history can all influence an opioid's subjective effects.

Keywords:   opioids, drug abuse, subjective effects, drug use

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