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Helmut Kettenmann and Bruce R. Ransom

Print publication date: 2004

Print ISBN-13: 9780195152227

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195152227.001.0001

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Gap Junctions and Hemichannels

Gap Junctions and Hemichannels

(p.177) 13 Gap Junctions and Hemichannels

Bruce R. Ransom

Zu-Cheng Ye

Oxford University Press

This chapter focuses on gap junctions and “half” gap junctions called hemichannels. The channels comprising a gap junction are large-diameter aqueous pores that extend from one cell, across the extracellular space, into an adjacent cell. These channels allow all inorganic ions and small organic molecules to diffuse freely from the interior of one cell into the interior of another cell. The general features of gap junctions and gap junctions in glial cells are discussed.

Keywords:   gap junction, channel, glial cells, half gap junctions, extracellular space

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