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Cancer Epidemiology and Prevention$
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David Schottenfeld and Joseph F. Fraumeni

Print publication date: 2006

Print ISBN-13: 9780195149616

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780195149616.001.0001

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Cancer Precursors

Cancer Precursors

Chapter:
(p.21) 3 Cancer Precursors
Source:
Cancer Epidemiology and Prevention
Author(s):

THOMAS E. ROHAN

DONALD E. HENSON

EDUARDO L. FRANCO

JORGE ALBORES-SAAVEDRA

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195149616.003.0003

The term “cancer precursor” refers to specific morphologic changes that precede the development of cancer. Knowledge of the etiology of cancer precursors varies considerably by anatomic site. In part, this might reflect the relative inaccessibility of a site to tissue sampling (e.g., ovary and pancreas) and hence the difficulty of detecting and diagnosing precursors at that site. This chapter describes some of the more well studied sites, for which there is substantial knowledge of the histopathology, epidemiology, and natural history.

Keywords:   precursor lesions, cancer development, cancer risk, morphologic changes, etiology of cancer

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