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Genetics and Public Health in the 21st CenturyUsing Genetic Information to Improve Health and Prevent Disease$
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Muin J. Khoury, Wylie Burke, and Elizabeth Thomson

Print publication date: 2000

Print ISBN-13: 9780195128307

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780195128307.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 12 July 2020

Genetics and prevention effectiveness

Genetics and prevention effectiveness

(p.329) 18 Genetics and prevention effectiveness
Genetics and Public Health in the 21st Century

Scott D. Grosse

Steven M. Teutsch

Oxford University Press

This chapter is intended to help the reader critically evaluate quantitative prevention-effectiveness studies in genetics and to understand their uses and limitations. No prior knowledge of prevention-effectiveness methods is assumed. The first part presents an overview of the major types of analysis, definitions, underlying concepts, and rules for carrying out prevention-effectiveness analyses. The second half of the chapter applies these rules to case studies of recent economic evaluations of genetic screening, genetic testing, and genetic-test-specific therapeutic interventions.

Keywords:   prevention-effectiveness analyses, public health, genetic testing, genetic screening, case studies

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