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Radiological Risk Assessment and Environmental Analysis$
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John E. Till and Helen Grogan

Print publication date: 2008

Print ISBN-13: 9780195127270

Published to Oxford Scholarship Online: September 2008

DOI: 10.1093/acprof:oso/9780195127270.001.0001

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The Role of Epidemiology in Estimating Radiation Risk: Basic Methods and Applications

The Role of Epidemiology in Estimating Radiation Risk: Basic Methods and Applications

Chapter:
(p.551) 13 The Role of Epidemiology in Estimating Radiation Risk: Basic Methods and Applications
Source:
Radiological Risk Assessment and Environmental Analysis
Author(s):

Owen J. Devine

Paul L. Garbe

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195127270.003.0013

This chapter provides an overview of methods used in epidemiologic investigations with a special emphasis on approaches pertinent to radiation-related epidemiology. It begins with a description of how the risk and rate of disease are estimated on the basis of observed disease counts. The discussion continues by examining measures of association used to evaluate potential relationships between these risk and rate estimates and exposure to a suspected causative factor. In addition, a discussion is provided on methods for evaluating the magnitude of an observed association between disease risk and exposure in light of the random variation expected in observable measures of disease burden. The chapter concludes with an examination of issues specifically related to epidemiologic investigations of exposures to radioactive materials, including the critical nature of appropriate dosimetric practice.

Keywords:   radiation risk, disease burden, risk measures, disease rates, risk estimates

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