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Molecular and Cellular Approaches to Neural Development$
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W. Maxwell Cowan, Thomas M. Jessell, and S. Lawrence Zipursky

Print publication date: 1998

Print ISBN-13: 9780195111668

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195111668.001.0001

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Molecular mechanisms of axon guidance and target recognition

Molecular mechanisms of axon guidance and target recognition

(p.108) 4 Molecular mechanisms of axon guidance and target recognition
Molecular and Cellular Approaches to Neural Development

Corey S. Goodman

Marc Tessier-Lavigne

Oxford University Press

This chapter discusses the molecular mechanisms that direct the initial migration of axons and establish the initial stereotyped patterns of projections and connections. It begins with a review of the cellular mechanisms that direct growing axons. It then presents an overview of the families of guidance molecules and receptors involved in this process. Finally, the chapter discusses the specific guidance events in which the precise guidance roles of different molecules have been defined through experimental analysis.

Keywords:   axons, projections, connections, cellular mechanisms, guidance molecules, receptors

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