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Molecular and Cellular Approaches to Neural Development$
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W. Maxwell Cowan, Thomas M. Jessell, and S. Lawrence Zipursky

Print publication date: 1998

Print ISBN-13: 9780195111668

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195111668.001.0001

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Neurotrophins and visual system plasticity

Neurotrophins and visual system plasticity

Chapter:
(p.509) 14 Neurotrophins and visual system plasticity
Source:
Molecular and Cellular Approaches to Neural Development
Author(s):

Carla J. Shatz

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195111668.003.0014

This chapter considers recent evidence suggesting that neurotrophins may function in the activity-dependent remodeling of connections during the development of the mammalian visual cortex. It begins by considering evidence of a requirement for a retrograde signal from the postsynaptic to the presynaptic neuron. It then reviews evidence that neurotrophins may be good candidates for this signal.

Keywords:   visual cortex development, neurtrophins, visual system, ocular dominant columns

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