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The Head-Neck Sensory Motor System$
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Alain Berthoz, Werner Graf, and P. P. Vidal

Print publication date: 1992

Print ISBN-13: 9780195068207

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780195068207.001.0001

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Vestibular N-Methyl-d-Aspartate Receptors in Normal and Compensated Guinea Pigs

Vestibular N-Methyl-d-Aspartate Receptors in Normal and Compensated Guinea Pigs

Chapter:
(p.625) Chapter 103 Vestibular N-Methyl-D-Aspartate Receptors in Normal and Compensated Guinea Pigs
Source:
The Head-Neck Sensory Motor System
Author(s):

Catherine De Waele

Nicholas Vibert

Alain Berthoz

Pierre Paul Vidal

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195068207.003.0103

The postural syndromes observed after unilateral global and selective lesions of the vestibular apparatus are discussed in the first part of this chapter. The second part includes the results that suggest that N-methyl-D-aspartate (NMDA) receptors contribute to the resting discharge of the vestibular neurons in normal guinea pigs in vivo. The third part contains the recommendation to increase the number and/or sensitivity of NMDA receptors on deafferented neurons in order to create denervation hypersensitivity. This could contribute to the functional recovery of the static reflexes in hemilabyrinthectomized guinea pigs.

Keywords:   postural syndromes, denervation hypersensitivity, receptors, deafferented neurons, static reflexes, vestibular neurons

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