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Palliative Care for Non-cancer Patients$
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Julia Addington-Hall and Irene Higginson

Print publication date: 2001

Print ISBN-13: 9780192629609

Published to Oxford Scholarship Online: November 2011

DOI: 10.1093/acprof:oso/9780192629609.001.0001

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Sickle cell disease

Sickle cell disease

Chapter:
(p.126) Chapter 10 Sickle cell disease
Source:
Palliative Care for Non-cancer Patients
Author(s):

Polly Edmonds (Contributor Webpage)

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780192629609.003.0011

Sickle cell disease (SCD) is a family of haemoglobin disorders characterised by chronic haemolysis (destruction of red blood cells), intermittent vaso-occlusion (occlusion of blood vessels), and marked variations in the character and severity of symptoms among individuals. SCD is now the second most common inherited disorder in the UK, with a prevalence of 0.23 per thousand births, and is associated with significant morbidity and mortality. This chapter reviews pathophysiology and current management strategies for SCD, the identification of patients with a poorer prognosis, and the role of palliative care in the management of these patients.

Keywords:   patient care, pathophysiology, inherited disorders, disease management

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