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The NMDA Receptor$
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G. L. Collingridge and J. C. Watkins

Print publication date: 1995

Print ISBN-13: 9780192625021

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780192625021.001.0001

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NMDA receptors, neuronal development, and neurodegeneration

NMDA receptors, neuronal development, and neurodegeneration

Chapter:
(p.428) 18 NMDA receptors, neuronal development, and neurodegeneration
Source:
The NMDA Receptor
Author(s):

JOHN GARTHWAITE

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780192625021.003.0018

In several brain regions, N-methyl-d-aspartate (NMDA) receptors are specially effective during the developmental period, where they appear to play important roles in the formation and stabilization of developing synapses. The early activation of NMDA receptors could also provide signals which promote neuronal survival, growth, and differentiation. This chapter attempts to review this area of NMDA receptor research and to place the information into a chronological framework.

Keywords:   neural development, NMDA receptors, neuronal survival, synapses, neuronal growth, neuronal differentiation

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