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The NMDA Receptor$
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G. L. Collingridge and J. C. Watkins

Print publication date: 1995

Print ISBN-13: 9780192625021

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780192625021.001.0001

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NMDA receptors and developmental plasticity in visual neocortex

NMDA receptors and developmental plasticity in visual neocortex

(p.313) 14 NMDA receptors and developmental plasticity in visual neocortex
The NMDA Receptor



Oxford University Press

Learning can be considered as a stimulus- and, hence, activity-dependent neuronal process that leads to a lasting change of stimulus-response relationships. The formation of a memory trace may thus be considered as a modification of the neuronal program that specifies input-output functions. This program is contained in the architecture of neuronal connectivity and in the transfer functions of these connections. Thus, any activity-dependent process that modifies, in a sufficiently stable and long-lasting way, the interactions between pairs of neurones could serve as a mechanism of learning.

Keywords:   NMDA receptors, neuronal processes, learning, memory traces, neuronal connectivity

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