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Migraine: A Spectrum of Ideas$
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Merton Sandler and Geralyn M. Collins

Print publication date: 1990

Print ISBN-13: 9780192618108

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780192618108.001.0001

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Contribution of experimental studies to understanding the pathophysiology of migraine

Contribution of experimental studies to understanding the pathophysiology of migraine

Chapter:
(p.21) 3. Contribution of experimental studies to understanding the pathophysiology of migraine
Source:
Migraine: A Spectrum of Ideas
Author(s):

J.W. Lance

G.A. Lambert

P.J. Goadsby

A.S. Zagami

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780192618108.003.0003

For any hypothesis to be truly satisfying, it must be compatible with all the known facts. The manifestations of migraine are so diverse that one must resist the temptation to seize on some and reject others in an attempt to justify a tenuous theory. Certain symptoms that can be recognized within the conceptual framework of migraine may be present in some episodes and not others, and may recur in certain phases of each attack but not in others. Each of these symptoms or groups of symptoms may have a different neurovascular basis.

Keywords:   experimental studies, pathophysiology, migraine, symptoms, neurovascular function, migraine attack

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