The first chapter begins with an example of an important series of pediatric research studies, the studies that led to the development of vaccines for rotavirus. This example illustrates the dilemma posed by pediatric research between protecting individual children and improving pediatric medical care. The chapter then explains the importance and prevalence of pediatric research and ends with a summary of the argument that we have an interest in contributing to valuable projects. This interest suggests that “nonbeneficial” pediatric research can be justified when it involves the participating children contributing to a valuable project to help others.
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