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Dielectric Relaxation in Biological SystemsPhysical Principles, Methods, and Applications$
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Valerica Raicu and Yuri Feldman

Print publication date: 2015

Print ISBN-13: 9780199686513

Published to Oxford Scholarship Online: August 2015

DOI: 10.1093/acprof:oso/9780199686513.001.0001

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Dielectric Models and Computer Simulations for Complex Aggregates

Dielectric Models and Computer Simulations for Complex Aggregates

Chapter:
(p.84) 1.3 Dielectric Models and Computer Simulations for Complex Aggregates
Source:
Dielectric Relaxation in Biological Systems
Author(s):

Valerică Raicu

Katsuhisa Sekine

Koji Asami

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199686513.003.0004

Modeling of the dielectric properties of random suspensions of individual particles described in Chapter 1.2 is taken a step further in this chapter toward taking specific structural features of biological systems into account. For instance, biological cells often form aggregates of various shapes, sizes, and packing degrees, and sometimes are connected to one another by small annular structures such as mitotic pores or gap junctions. This chapter overviews both the analytical and numerical efforts aimed at predicting the dielectric dispersion curves for aggregated systems of cells. The analytical methods rely on approximations aimed at incorporating near-field effects into the equivalent dielectric permittivity of a suspension of aggregated particles, while the numerical methods are based on solving electrical potential distributions in the aggregates using computer algorithms.

Keywords:   dielectric dispersion, dielectric modeling, near-field effects, cell aggregation, analytical models, numerical methods

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