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AlcoholScience, Policy and Public Health$
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Peter Boyle, Paolo Boffetta, Albert B. Lowenfels, Harry Burns, Otis Brawley, Witold Zatonski, and Jürgen Rehm

Print publication date: 2013

Print ISBN-13: 9780199655786

Published to Oxford Scholarship Online: May 2013

DOI: 10.1093/acprof:oso/9780199655786.001.0001

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Alcohol and carcinogenesis: mechanisms and biomarkers

Alcohol and carcinogenesis: mechanisms and biomarkers

Chapter:
(p.211) Chapter 24 Alcohol and carcinogenesis: mechanisms and biomarkers
Source:
Alcohol
Author(s):

C.J. Peter Eriksson

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199655786.003.0024

Alcohol consumption has been associated with cancers in various locations in the body including the upper aerodigestive tract, stomach, intestinal tract, liver, pancreas, bladder, lung, prostate, and female breast. Alcohol drinking-related cancer is not caused by alcohol per se. Instead, the mechanistic explanations include the metabolism of alcohol, other ingredients in the drink, and/or more indirect pathways related to lifestyle factors associated with alcohol consumption. Genetic epidemiology research is becoming a more and more important tool in assessing the aetiology and biomarkers of alcohol-related cancers. This chapter summarizes the current knowledge regarding these aspects.

Keywords:   alcohol consumption, alcohol use, cancer risk, alcohol metabolism, genetic epidemiology

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