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Epilepsy and Memory$
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Adam Zeman, Narinder Kapur, and Marilyn Jones-Gotman

Print publication date: 2012

Print ISBN-13: 9780199580286

Published to Oxford Scholarship Online: September 2012

DOI: 10.1093/acprof:oso/9780199580286.001.0001

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The syndrome of transient epileptic amnesia

The syndrome of transient epileptic amnesia

Chapter:
(p.139) Chapter 8 The syndrome of transient epileptic amnesia
Source:
Epilepsy and Memory
Author(s):

Adam Zeman

Chris Butler

John Hodges

Narinder Kapur

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199580286.003.0008

Epilepsy reflects a disturbance of a fundamental aspect of brain function, the synchronized rhythmic activity of large populations of neurons. As human memory also depends upon the synchronized rhythmic activity of large populations of neurons, it should not be surprising that epilepsy is commonly associated with memory disturbance, nor that there is an intimate relationship between the brain mechanisms for memory in the medial temporal lobes (MTLs) and the pathogenesis of seizures. This chapter reviews what is known of the disruptive effects of a variety of seizure-types on memory, before focusing on a form of epilepsy of which, unusually, the main manifestation is amnesia.

Keywords:   epilepsy, brain function, neurons, memory disturbance, medial temporal lobes, seizures

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