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Insect Infection and ImmunityEvolution, Ecology, and Mechanisms$
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Jens Rolff and Stuart Reynolds

Print publication date: 2009

Print ISBN-13: 9780199551354

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780199551354.001.0001

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Recognition and response to microbial infection in Drosophila

Recognition and response to microbial infection in Drosophila

(p.13) CHAPTER 2 Recognition and response to microbial infection in Drosophila
Insect Infection and Immunity

Nichole A. Broderick

David P. Welchman

Bruno Lemaitre

Oxford University Press

This chapter discusses the mechanisms whereby Drosophila recognize foreign microbes, the signalling systems that regulate adapted responses against them, and the effector mechanisms used to control them. It first focuses on the so-called systemic antimicrobial response. The second section of the chapter looks at local immune response, particularly gut epithelial immunity. The final section of the chapter discusses current research themes exploring the integration of local and systemic immunity, as well as their integration in host physiology.

Keywords:   Drosophila melanogaster, insect immunity, antimicrobial response, local immune reponse, gut epithelial immunity, antimicrobial peptides

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