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Concepts of EpidemiologyIntegrating the ideas, theories, principles and methods of epidemiology$
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Raj Bhopal

Print publication date: 2008

Print ISBN-13: 9780199543144

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780199543144.001.0001

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Variation in disease by time, place, and person

Variation in disease by time, place, and person

A framework for analysis of genetic and environmental effects

Chapter:
(p.47) Chapter 3 Variation in disease by time, place, and person
Source:
Concepts of Epidemiology
Author(s):

Raj S. Bhopal

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199543144.003.0003

This chapter emphasizes a systematic framework of analysis of disease variations, particularly to ensure that observations of variation are real, and not products of data errors and artifacts. The framework applies to all measures of disease frequency. Topics discussed include reasons for analysing disease variations: environment and genetics; introducing human genetic variation and genetic epidemiology; disease clustering and clusters in epidemiology; and applications of observations of disease variation.

Keywords:   data errors, artifacts, disease incidence, disease variations, disease clusters

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