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Cognitive Neuroscience of AgingLinking Cognitive and Cerebral Aging$
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Roberto Cabeza, Lars Nyberg, and Denise C. Park

Print publication date: 2016

Print ISBN-13: 9780199372935

Published to Oxford Scholarship Online: December 2016

DOI: 10.1093/acprof:oso/9780199372935.001.0001

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The Modifying Role of Hypertension in Cognitive and Brain Aging

The Modifying Role of Hypertension in Cognitive and Brain Aging

(p.389) 15 The Modifying Role of Hypertension in Cognitive and Brain Aging
Cognitive Neuroscience of Aging

Karen M. Rodrigue

Gérard N. Bischof

Oxford University Press

Approximately 67% of adults over age 60 are hypertensive, and the brain is an early and critical target of the disease, The neural degradation that results from hypertension has significant effects on cognitive function and many cognitive aging researchers are unaware of this relationship. Hypertension affects brain structure, resting cerebral blood flow, and brain function, which in turn, negatively affects cognition. Hypertension also plays a role in in neuropathology, and its relationship to Alzheimer’s disease in particular is discussed. The role of vascular health and disease to cognitive aging is thoroughly reviewed.

Keywords:   cognitive aging, hypertension, vascular health, brain structure, cognitive neuroscience

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